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It develops when there is excess fat in liver cells due to too much fatty acid uptake in the liver, excess synthesis of fat in the liver, and not enough fat exported out of the liver

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10.1111/j.1753-4887.2012.00505.x Nutr

The best defense is proactive: encourage strength training and adequate protein from the very beginning so that patients preserve muscle while they lose weight

Importantly we still do not know the impact they will have on patients who take them long-term